Platelet rich plasma mechanism uses the regenerative and healing properties of platelets. These have the ability to locally release growth factors, small molecules that act as true messengers to activate the initiation of the mechanisms of skin regeneration.
Plasma contains essential factors for cell survival, such as nutrients, vitamins, hormones, minerals, and proteins. Among the plasma proteins are the vital molecules for coagulation and the generation of a fibrin clot that serves as a guide for cell migration, differentiation, and proliferation.
Injection of platelet-rich plasma is a treatment indicated for patients who want rejuvenation and embellishment of the skin, especially the face, neckline, back, and hands.
Platelet rich plasma in wound healing
Platelet-rich plasma (PRP) is one of the fastest skin wound treatment mechanisms; it’s natural and effective. There are no side effects and recently it has become the default treatment to accelerate healing of all kinds. Studies suggest that it shows wonderful results in the treatment of ulcerative wounds.
It is this natural ability to heal tissue through autologous growth factors that make plasma injections successful. In fact, the injection of PRP gives the tissues the same signal as if there had been an injury, inducing a mechanism of tissue repair similar to healing.
Wound healing is a dynamic and interactive process involving multiple cells and proteins that interact sequentially in an integrated series of cellular, physiological, biochemical and molecular events. This fragile balance can be interrupted by some factors, including the presence of infection, ischemia, and trauma. These factors can increase the level of proinflammatory cytokines, which triggers an increase in cellular levels of metalloproteinases, and the resulting decrease in tissue growth factors can delay healing.
The human body heals naturally through a complex process during which cells undergo a series of biological changes to facilitate hemostasis, fight infections, migrate to the wound space, deposit a matrix, form new blood vessels and contract.
A healthy wound needs a moist environment, an adequate infusion (blood flow) for the supply of nutrients and cellular sources of growth factors, cytokines, and chemokines to heal naturally.
This new system restores the natural balance of chronic and repair; the patented biodynamic formulation provides:
Fibrin derived from plasma and fibronectin scaffolding for tissue repair.
Gel releases platelets that contain growth factors, cytokines, and chemokines to stimulate healing.
Improvement of collagen synthesis and elimination of harmful free radicals.
Restore the balanced environment that is lacking in chronic wounds.
Treatment frequency
The duration of bio-dynamic therapy for the treatment of chronic wounds will vary depending on the area and the depth of the wound. This treatment works perfectly when combined with standard care procedures for comprehensive wound management such as:
- Elimination of necrotic or infected tissue
- Control of blood sugar in diabetes
- Use of a negative pressure suction bandage
- Compression therapy for venous stasis ulcers
- Establishment of an adequate blood circulation
- Maintain a moist wound environment
- Management of wound infection
- Cleaning of wounds
- Nutritional support, glycemic control in subjects with diabetic ulcers
- Management of the underlying disease
