Of the many cell types in amniotic fluid, the two cell types that have been identified by various research groups as having great therapeutic potential in regenerative medicine are amniotic fluid mesenchymal stem cells (AF MSC) and amniotic epitheilal cells (AEC)
Regarding amniotic fluid mesenchymal stem cells…. They exhibit the potential to repair and regenerate damaged tissue along with immunomodulatory properties. At P is one of the most attractive tools for clinical application based on cell therapy that exhibit antiation.
Potential similar to that of bone marrow derived mesenchymal stem cells.
Safety of amniotic fluid mesenchymal stem cells despite their high proliteration rate. AFMSC retain a normal karyotype and do not display any tumourigenic potential even after exten sive expansion in cell culture
Visibility of stem cells through cry
According to multiple research art fluid mesenchymal stem cells remains stable through multiple passages of cells culturing enduring the freezing and thawing process very well
Amniotic fluid contains a variety of nutrients that encourage soft tissue healing these nutrients are essential for effective tissue regeneration
Concentration and components
Amnyo Fluid and amnyo factor are both rich in al the natural components of amniotic fluid. Amnyo Factor is 100% concentrated with no dilution from cryoprotective agents. Amnyo fluid is minimally diluted with only a 10% dilution of cryoprotective agents to assist in maintaining cell visibility during amnyo fluid and emnyo factor are both derived from genuine amniotic fluid and offer exceptional medical benefits to patients
Amniotic fluid contains a measurable concentration of various growth factors that stimulate and facilitate tissue healing and regeneration. Some growth factors incluse:
Epidermal growth factor involved in cell growth and would healing
Transforming growth Alfa (TGF- a) encourages cell proliferation growth in wounded tissues and cellular development)
transforming growth factor beta 1(TGF-B1) Facilitates cell proliferation growth in wounded tissues insulin- like growth factor 1(IGF-1) – Critical to growth and development
Granulocyte colony stimulating factor (G-CSF) imitates the Production of granulocytes and stem cells within bone marrow which is eventually released into the blood stream
Cytokines are special proteins that communicate with tissues in various capacities. These Mechanisms Often lead to a reduction in inflammation and pain Provoking great value to the orthobiologics field. A number of these inherent cytokines include:
Erythropoietin (EPO) – stimulates red blood cell production for oxygenation needed to heal wounded tissues.
Interleukin 1 beta (IL-16) key mediator during inflammatory responses
Interleukin 6 (IL-6) acts as an anti-inflammatory signaling molecule during wound healing
Tumor necrosis factor alpha (TNF-a) signaling protein involved in systemic inflammation as well as a mediator during the acute phase of the wound healing response.
Why amniotic Fluid?
Glad you asked.
Amniotic fluid has a phenomenal worldwide reputation as being the perfect regenerative medicine product. It has a wide range of growth factors, cytokines, beneficial proteins, cells, and nutrients. It is nature’s own recipe for tissue growth and regeneration.
Don’t mess with perfection!
We believe that amniotic fluid is perfect the way it is. We also believe that there is little benefit to altering/manipulating amniotic fluid, other than simple cryopreservation to maintain fluid stability for storage and use excess manipulation, as seen in most other companies, is mostly for the appearance of being better than nature’s original fluid. Why mess with perfection.